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青科沙龙第133期 | Nature-CRISPR-Cas9 筛选揭示神经-免疫调控新机制
其次,利用CRIPSR-Cas9基因筛选系统进行小鼠T细胞体内和体外分化的基因功能筛选,并按照基因的功能进行排序,鉴定Th1分化的正向调节因子RAMP3。RAMP3能够与CRLR蛋白在细胞表面形成神经递质CGRP/ADM的受体,但是RAMP3在T细胞 ...
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