Open and endoscopic carpal-tunnel releases are commonly used as the definitive treatment for carpal tunnel syndrome. This ...

New catheter materials for peripherally inserted central catheters (PICCs) may reduce the risk of device failure due to infectious, thrombotic, and catheter occlusion events. However, data from ...

A 14-year-old patient presented to the ED with a 12-month history of joint pains and a 2-month history of headaches and ...

Allogeneic hematopoietic stem-cell transplantation is the only curative treatment for myelofibrosis. Driver mutations are the pathophysiological hallmark of the disease, but the role of mutation ...

Talquetamab is a T-cell–redirecting bispecific antibody targeting G protein–coupled receptor class C group 5 member D (GPRC5D). 13-15 In the MonumenTAL-1 study, more than 71% of the patients ...

The continuous emergence and reemergence of tickborne diseases have presented an increasing threat to human health. 1,2 We conducted an active surveillance of febrile patients with recent tick ...

The Race and Medicine collection reflects NEJM’s commitment to understanding and combating racism as a public health and human rights crisis. Our commitment to antiracism includes efforts to ...

Dr. Annie Liu (Medicine): A 35-year-old woman was admitted to this hospital because of shortness of breath and edema in the legs. Eight weeks before the current presentation, the patient was ...

Multiple diseases in children have been linked to manufactured synthetic chemicals, which are subject to few legal or policy constraints. A revamping of law and restructuring of the chemical ...

This Journal feature begins with a case vignette highlighting a common clinical problem. Evidence supporting various strategies is then presented, followed by a review of formal guidelines, when ...

Prevention of drug-resistant tuberculosis is a global health priority. However, trials evaluating the effectiveness of treating Mycobacterium tuberculosis infection among contacts of persons with ...